By exploiting the natural affinity of the Shiga toxin for these receptors, researchers have developed toxin-based nanocarriers to target various cancer types [22,23,24,25] As a proof of concept, we decided to functionalize latex nanoparticles of 400 nm with the non-toxic subunit B (StxB) of the Shiga toxin for specific targeting of GB3-expressing cells. Here, PPIB is linked to cancer.