VDAC1 and breast carcinoma: MCF-10A cells transfected with pmOGT-HaloTaq showed a significant decrease in VDAC1, VDAC2, and VDAC3 mRNA levels, whereas in MDA-MB-231 and Hs578t breast cancer cells only VDAC3 and VDAC1 mRNA levels decreased significantly after mOGT upregulation (Figure 5A).