The following secondary genetic changes are observed: monosomy of chromosomes 13, 14, 17 (15–50% of patients with MM), translocations involving the MYC gene: t(8,14); t(8,11)—in 15% of patients and in 10–40% of them—deletions including the genes: CDKN2C and FAM46C (1p), CD27 (12p), RB1 and DIS3 (13p), TRAF3 (14p), TP53 (17p). The gene discussed is MYC; the disease is Miyoshi myopathy.