ATP5IF1 and cancer: Figure 4 summarizes the effect of IF1 dose on ΔΨm in cancer and non-cancer cells when the mitochondrial content of IF1 is manipulated by its silencing, by knocking it out or by its overexpression, both in transient and in stable transfectants, as well as in primary neuronal cultures of genetically modified mouse models of loss- and gain-of-function of IF1 in forebrain neurons, supporting the participation of IF1 in the upregulation of ΔΨm.