Gastrointestinal stromal tumors (GIST) are rare mesenchymal malignancies of the gastrointestinal tract that are characterized by the frequent presence of oncogenic driver mutations in the KIT gene, which encodes the receptor tyrosine kinase c-KIT, and in the PDGFRA gene encoding the platelet-derived growth factor receptor α (PDGFRα) [1]. Here, NTRK1 is linked to gastrointestinal stromal tumor.