Another distinctive example in our study is the common loss&CN-LOH of ERBB4 and several other tumor suppressor candidates (hotspot #14), while tumor studies point to more prevalent involvement of ERBB2 and ERBB3. Finally, loss&CN-LOH of CDKN1B (hotspot #15) is frequent in our results, but tumor-related analyses are pointing to another member of cyclin-dependent kinases, such as CDKN2A. The gene discussed is ERBB3; the disease is neoplasm.