With regards to EGFR-mutant (EGFRm) NSCLC, a meta-analysis of 40 studies estimated a pooled sensitivity of 68% (95% CI = 60–75%) and specificity of 98% (95% CI = 95–99%) for EGFR mutation detection in ctDNA [17]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.