For example, immunohistochemical staining of p16ink and p53 in 12 cases of Warthin’s tumor was negative in all cases, suggesting that there was no evidence of abnormal staining for tumor suppressor gene protein products (p16ink and p53) and no evidence of consistent clonal allelic deletions, indicating that Warthin’s tumor is non-neoplastic [104]. The gene discussed is TP53; the disease is Warthin tumor.