JAK2 and breast cancer: On the other hand, the lncRNA MAFG-AS1 (MAF BZIP transcription factor G antisense RNA 1) promotes proliferation and metastasis of breast cancer by different mechanisms (Figure 2, right top), such as modulating the STC2 (Stanniocalcin 2) pathway and activating the JAK2/STAT3 (Janus kinase 2/signal transducer and activator of transcription 3) pathway through the miR-3196/TFAP2A axis [54,55].