Chronic kidney disease (CKD) is one of the most common complications of type 2 diabetes (T2D), affecting ~50% patients worldwide, and is defined by the presence of either estimated glomerular filtration rate (eGFR) persistently <60 ml/min/1.73 m2 and/or sustainedly elevated urinary albumin excretion (urine albumin-to-creatinine ratio (UACR) > 30 mg/g) [1]. The gene discussed is ALB; the disease is chronic kidney disease.