In accordance with our findings in macrophages, P2Y11/IL-1R- or P2Y11/CXCR7-driven CCL20 production in astrocytoma cells depended on EGFR as well as on ERK (Fig. S7) and appeared to occur in an EGFR/CXCR7-ligand-independent manner (Fig. S8). Here, P2RY11 is linked to astrocytoma (excluding glioblastoma).