For identification of the cell composition of psoriatic skin, 13 samples were collected in this study, 4 imiquimod-induced psoriatic mouse samples (IMQ group), 5 wild-type mouse samples (WT group), 2 mouse samples that were induced by imiquimod and treated with SHP099 hydrochloride for an additional 4 days (SHP099 group), 1 Chrna5 knockout mouse sample (KO group), and 1 Chrna5 knockout imiquimod-induced psoriasis sample (KO IMQ group). The gene discussed is CHRNA5; the disease is psoriasis.