MAPT and Alzheimer disease: However, when looking at MCI+ and AD participants only, p-tau217+ (Janssen) better correlated with neocortical tau PET (rneocort. = 0.72, P < 0.0001, 95% CI = 0.59–0.81, S > 13.28, Spearman correlation) then did the ALZpath (rneocort. = 0.61, P < 0.0001, 95% CI = 0.45–0.73, S > 13.28, Spearman correlation) assay (P = 0.044; 95% CI = 0.004–0.23, S = 4.50) (Supplementary Fig. S4).