Furthermore, neutralization of IL-17C reduces skin inflammation in the IL-23–elicited mouse model of Ps and in the calcipotriol-induced (MC903) and flakey tail strain mouse models of AD, and it reduces the proinflammatory mediators HBD2, IL-36γ, and LCE3A in human lesional skin explants of Ps and atopic eczema (7, 9). Here, IL17C is linked to atopic eczema.