IL17C and psoriasis: Indeed, a motif known to interact with TCF4 (5’-CAGGTG/CACCTG-3’) was more abundant in the 2 kb promoter region of the 191 IL17C-correlated genes as compared with all other genes expression in lesional skin of patients with psoriasis (PP) (P = 5.40 × 10–9, FDR = 1.47 × 10–6) (Supplemental Figure 4).