In Ps and AD lesional skin, IL17C positively correlates with NFKBIZ (r = 0.46, P = 8.7 × 10–7, Ps; r = 0.66, P = 0.001, AD; Figure 4A), and TCF4 negatively correlates with ZC3H12A (r = –0.53, P = 7.0× 10–9, Ps; r = –0.43, P = 0.05, AD; Figure 4A). Here, ZC3H12A is linked to Alzheimer disease.