RAB5A and breast carcinoma: The aberrant expression of RAB5A has been widely documented in various human tumors, e.g. breast cancer, lung cancer, and ovarian cancer; furthermore, the expression of RAB5A is tightly associated with tumorigenesis and metastasis (Yu et al. 1999, Su et al. 2007, Zhao et al. 2010, Yang et al. 2011).