The results indicate that the expression of the genes of CDK2, CDK5, CDK5RAP2, CDK11A, CDK11B, CDK20, CDKN2A, and E2F3 was significantly upregulated in NAM and the expression of the genes of CDK7, CDK8P2, CDK16, CDKAL1, CDH1, E2F6, E2F8, and MITF was significantly upregulated in AM. The gene discussed is CDK11A; the disease is acute myeloblastic leukemia with maturation.