IL10 and cystic fibrosis: This potential tolerance phenotype was confirmed at the transcriptional and protein levels (Figures 5, 6, Supplementary Figure S6-S8), when all cells (and not only Lin+ cells) were analysed, showing increased background levels of cytokines in CF PBMCs, combined to a reduced inducibility by PMA/iono, with the notable exception of IL-10, at the RNA level (Figure 5).