The expression of genes associated with tumor promotion such as Snap29 (30), Mcoln1 (31) and Nek6 (32) was up-regulated in peritoneal CLL cells from TCL1-Tg mice compared to CLL cells from TCL1-Tg BAFF-/- mice (Figure 6C). This evidence concerns the gene MCOLN1 and B-cell chronic lymphocytic leukemia.