It has already been shown that aortic aneurysms are associated with increased recruitment of monocytes to aneurysms, and this is promoted by upregulating I-CAM, V-CAM, MCP1, and MMP2 (25) and over-expressing the matrix metalloproteinase family (MMP) (53), all contributing to vessel remodeling. Here, MMP2 is linked to aortic aneurysm.