Immune, Cognitive, and Functional Consequences of mTOR inhibition in the elderly (including assessment of cardiac function) (Phase 2, NCT04742777) (Phase 2, NCT02874924) Angiofibromas in Tuberous sclerosis (Phase 2, NCT01526356) Alzheimer’s and Cognitive Health (Phase 2, NCT04629495). The gene discussed is MTOR; the disease is Angiofibroma.