ACE2 and COVID-19: Over the past few decades, a good amount of evidence supports erectile function as an excellent indicator of systemic health in general and vascular health in particular (46), effects of COVID-19 on the cardiovascular system (i.e., acute cardiac injury, myocarditis) as well growing evidence in the role of endothelial cell dysfunction during COVID-19 infection most importantly, the endothelium expresses the ACE2 led many have hypothesized there may be an increased risk of Erectile dysfunction (ED) following COVID-19 (47).