Afterward, univariate Cox regression analysis was performed to evaluate the prognostic value of each tryptophan metabolism-related gene in the TCGA ovarian cancer cohort, with IDO1, ALDH3A2, HADHA, OGDHL associated with risk values, and CAT, WARS1 involved in protective factors (Additional file 1: Fig. S5b). The gene discussed is ALDH3A2; the disease is ovarian cancer.