Similarly, of the 5600 CD8+ T-cell PEPs from SARS-CoV-2 proteome, only 523 peptides could detect positive CD8+ T cell responses in 99 patients with SARS-CoV-2 infection [18], while 29 of 499 PEPs from hepatocellular carcinoma (HCC)-associated antigens presented positive T cell responses in 46 HCC patients [20]. Here, CD8A is linked to hepatocellular carcinoma.