GLP1R and myotonic dystrophy type 2: Two classes of medications designed as novel therapeutic strategies for DM2, namely Glucagon-Like Peptide-1 receptor agonists (GLP-1Ra) and Sodium-glucose cotransporter-2 inhibitors (SGLT2i), have demonstrated to reduce CV mortality and the occurrence of heart failure (HF) in patients with DM2 [8–10].