The glucocorticoid receptor gene NR3C1 is also implicated in multiple neurological NCDs including SCZ [7] and is a predictor of poor prognosis in estrogen receptor (ER) breast cancer [37] Indeed, longitudinal studies with second generation antipsychotics show that their mechanism is strongly linked to renormalizing methylation changes associated with SCZ [32]. The gene discussed is NR3C1; the disease is breast carcinoma.