TAS2R63P and neoplasm: Notably, these allograft models have been commonly exploited in cancer immunology to investigate antitumor immunity and MDSCs in immune-competent wild-type mice.19,20 Mice were subcutaneously implanted with each cancer cell line, and brain tissues of tumor-bearing mice were then processed for the immunostaining of phospho-ribosomal protein S6 (p-S6), a specific marker for neuronal activation.21 We comprehensively assessed brain regions ranging rostrocaudally from olfactory bulbs to the brainstem.