Preliminary histology results from cases of sporadic ALS who were treated with CuII(atsm) provide some evidence for translatability of outcomes from mutant SOD1 mice to the human sporadic disease1,3,4,43, and when used as a PET tracer, CuII(atsm) selectively accumulates in the affected motor cortex of sporadic ALS patients. This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.