Many qFTs were down-regulated upon anti-TGF-β Ab treatment associated with collagen content (e.g. skeleton notes and branches, total collagen area ratio, assembled collagen, total density area ratio), morphometry (e.g. total skeleton length, perimeter, area and width) and architecture (e.g. normalized count of uniform inertia, normalized count of contrasted inertia, mean and median inertia, kurtosis and skew) sub-phenotypes of fibrosis (Supplementary Table 2). The gene discussed is TGFB1; the disease is fibrosis.