We analyzed the expression correlation of all genes with GINS2 based on TCGA-Glioma (n = 691) and CGGA-Glioma (n = 590), and obtained 411 and 203 genes positively correlated with GINS2 expression (R > 0.6, P < 0.05), respectively, and intersected them with 310 up-regulated genes obtained from RNA sequencing, with 34 intersected genes being presented (Supplementary Fig. 5). The gene discussed is GINS2; the disease is central nervous system cancer.