Analysis of The Cancer Genome Atlas (TCGA) [21] showed a systematic upregulation of NFYC-AS1 in most human tumors as compared to normal tissues, including the main histotypes of non-small cell lung cancer (NSCLC), lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC) (Fig. 1A). This evidence concerns the gene NFYC and lung adenocarcinoma.