Last, we isolated tumor-infiltrating CD8+ CAR T cells at 38 days (i.e., 1 month after CAR T cell injection) and we found an increased although not significant (p = 0.06) number of Rapa-CD8CAR cells in s.c. tumors compared with ctrl-CD8CAR cells (Fig. 7G). The gene discussed is CD8A; the disease is neoplasm.