However, when these tumor cells were co-cultured with either Δ133p53α T cells or, separately, with full-length p53α T cells at 10 target-to-T cell ratios, only the Δ133p53α T cells showed 99 out of 100 genes that were down-regulated and these genes were p53 regulated (inducible) genes. Here, TP53 is linked to neoplasm.