PERM1 and androgen insensitivity syndrome: At the same time, compared with model group, the expression of NLRP3, ASC, Caspase-1 was significantly down-regulated and PERM1 was significantly up-regulated in the vector-miR-214-3p inhibitor and lnc_AABR07044470.1 over-expression groups (Fig. 5F–J), this was consistent with the experimental results of the AIS animal model, indicating that over-expression of lnc_AABR07044470.1 and inhibition of miR-214-3p expression could relieve the neuronal injury in the hypoxia/reoxygenation cell model.