AKT1 and neoplasm: The identification of this signaling pathway highlights various types of chemokines and their receptors, as well as the mechanism by which chemokine signaling activates the JAK/STAT, Ras, ERK and Akt pathways and interactions of signaling pathway proteins such as CX3CR1 and CXCL10 to regulate tumor cell proliferation, migration, invasion and cell cycle progression.