Specifically, it has been shown that intake of Lactobacillus acidophilus INMIA 9602 Er-2 strain 317/402 has positive effects, including the normalization of serum C-reactive protein levels in FMF patients during remission (Pepoyan et al., 2015; Pepoyan et al., 2017; Balayan et al., 2015). This evidence concerns the gene CRP and familial Mediterranean fever.