CYSLTR1 and Cerebral ischemia: Cysteinyl leukotriene receptor (CYSLTR) modulates overall neuroinflammatory and repair processes of cerebral ischemia, such as microglial inflammation, blood-brain barrier leakage, and glial scar formation, and its antagonists could attenuate neuronal damage and activation of microglia and astrocytes in rats 44,45.