It is also consistent with reports from other related studies, such as the GSE26887 dataset from the GEO database, which showed that lncRNA-ZFAS1 was significantly upregulated in DM patients with comorbid HF compared with DM patients, whereas downregulation of ZFAS1 led to a protective effect on cardiomyocytes during myocardial infarction. This evidence concerns the gene ZFAS1 and diabetes mellitus.