AFP and Cirrhosis: In addition, Cirrhosis (adjusted HR = 1.8541, 95% CI: 1.1379–3.0213, p = 0.013), size of tumor ≥5 cm (adjusted HR = 1.9713, 95% CI: 1.5209–2.5550, p < 0.001), AFP ≥400 ng mL (adjusted HR = 1.8929, 95% CI: 1.4668–2.4428, p < 0.001), and a high serum CRP concentration (adjusted HR = 1.0053, 95% CI: 1.0024–1.0083, p < 0.001) were independent risk factors (Table 3).