- The secretion of EpCAM BiTE has been shown to effectively promote activation of T cells.- The VV-EpCAM BiTE demonstrates enhanced antitumor activity in EpCAM-expressing breast cancer.- Both VV-EpCAM BiTE and VV-Ctrl exhibit similar anticancer properties in the EpCAM-negative carcinoma model. The gene discussed is EPCAM; the disease is carcinoma.