- Supernatants from OVV-CD19 BiTE -infected cells induces the activation and proliferation of T lymphocytes.- Long-term tumor remissions without recurrence noted.- OVV-CD19 BiTE triggers T cells proliferation and recruited this lymphocytes to the tumor sites.- OVV-CD19 BiTE has higher anticancer activity than parental virus and blinatumomab. This evidence concerns the gene CD19 and neoplasm.