The two-sample MR analysis showed that the expression of PAFAH1B1, IFNGR1, CDK13, ZZEF1, FNBP4, SLC38A1, UBL3, MT2A, ANP32E, TNIP1, ADAR, MIDN, and E2F4 was potentially associated with the prevalence of AD (Figure 7A). The gene discussed is PAFAH1B1; the disease is Alzheimer disease.