Notably, correlation analysis revealed a significant negative association between SOD and CRP (r = -0.535, p < 0.001), IL-6 (r = -0.453, p < 0.001), LDH (r = -0.498, p < 0.001), and Ferritin (r = -0.460, p < 0.001) (Figure 3B), suggesting a direct connection between oxidative stress and the inflammatory response in COVID-19. This evidence concerns the gene CRP and COVID-19.