EGFR and non-small cell lung carcinoma: The LAURA trial, which is in progress (NCT03521154), is a randomized phase III, double-blind, placebo-controlled, that is currently assessing the efficacy and safety for osimertinib, a third-generation irreversible oral EGFR-tyrosine kinase inhibitor, as a maintenance for unresectable NSCLC after CRT, with exon 19 deletion (ex19del) or Leu858Ar (L858R) EGFR mutations [22].