This warranted further study as cDC1s are a cDC subtype which expresses XCR1 and is involved in cross-presentation and CD8+ T cell-mediated anti-tumor responses.61-63 An increase in total surface expression of XCR1 was also observed in cultured cDCs treated with apilimod compared to dimethyl sulfoxide (DMSO) (Supp. This evidence concerns the gene CD8A and neoplasm.