EGF and COVID-19: In contrast, urine EGF concentrations increased by an average of 7% per day (95% CI 4.1% −10.0 per day) in the COVID-19 negative group but by only 0.5% per day (95% CI −1.1% to +2.2% per day) in COVID-19 positive group (p-value for interaction <0.001).