To circumvent cardiomyopathy associated with prolonged Bmal1 deletion, we generated an inducible cardiomyocyte-specific Bmal1 knockout mouse line (Bmal1loxP/loxP Myosin Cre+ mice) by crossing Bmal1 floxed (Bmal1loxP/loxP) mice with Myosin Cre+ mice. Here, BMAL1 is linked to cardiomyopathy.