GSTM1 and schizophrenia: To evaluate SCZD-associated gene expression differences unique to Hb-enriched tissue compared to other brain regions, we conducted a cross-region comparison of DEGs obtained from our Hb-enriched dataset (n=45 DEGs, FDR < 0.05) and those from previously published bulk RNA-seq studies of four other brain regions: dorsolateral prefrontal cortex (DLPFC), hippocampus, dentate gyrus, and caudate 19–21 (Fig 4E).