At the same time, PAICS level were related to tumor metastasis, EGFR status and gender in NSCLC patients based on TCGA database (Figures 2D, E, and S2A, left), whereas uncorrelated with tumor metastasis, EGFR status and gender from microarray analysis (Figures 2D, E, and S2A, right). The gene discussed is PAICS; the disease is non-small cell lung carcinoma.