TOX3 and hepatocellular carcinoma: The lung metastasis model of HCC in nude mice was established by using HCCLM3 cells, and the results of small animal live imaging system chemiluminescence showed that the fluorescence signal in the lung area was substantially decreased after the TOX3 knockout (Figure 3D), and the lung metastases after the TOX3 knockout were also decreased (Figure 3E).