CD38 and colorectal carcinoma: Following both univariate and multivariate Cox regression analyses, the histologic grade (G2) (HR = 3.14; p = 0.01), LVI (HR = 3.98; p < 0.01), and higher proportion of CD38+ NK cells (HR = 2.37; p = 0.03) were identified as independent risk factors for poor prognosis of CRC.