Qu et al (185), demonstrated that DACT3-AS1 expression was reduced in GC and associated with low prognosis in GC patients, and the results of in vitro and in vivo experiments revealed that DACT3-AS1 inhibited cell proliferation, migration and invasion by targeting the miR-181a-5p/sirtuin 1 (SIRT1) axis. The gene discussed is SIRT1; the disease is gastric cancer.